Mood and DMN 2gps
Jason
OVERVIEW
Question this study addresses:
are there any factors that differentiate healthy controls (HC) and chronic low back pain (CLBP) patients?
Measures analyzed
- Pittsburg Sleep Questionnaire
- Epsworth Sleepiness Scale
- Insomnia Severity Index
- McGill Pain Questionnaire
- Beck Depression Inventory
- Pittsburg Sleep Questionnaire
NOTE: THE ANALYSES CONTAINED HEREIN WILL BE FOR A MANUSCRIPT BASED ON APS 2017.
ADDITIONAL ANALYSES AND RESULTS FOR THE POSTER WILL BE IN A DIFFERENT FILE.
FIX THE TEXT BELOW
ABSTRACT
Title
Significant differences in sleep and depression among chronic pain groups: Implications for patient education
Purpose
START
DATA
Import data from GitHub
PSQI
The global PSQI score is then calculated by totaling the seven component scores, providing an overall score ranging from 0 to 21, where lower scores denote a healthier sleep quality.
A PSQI Global score ≥ 5 is the clinical cutoff score (i.e., sleep problems)
The PSQI data has been updated, processed, clean and scored
NOTE: I need to add a section that discusses the PSQI cutoff. Anything over “5” is considered significant.
INITIAL DATA SETS
Create a small dataset (dat.sm) that includes only the variables of interest.
VARIANCE CHECK
Which variable(s) in the dat.sm data has potential issues with variances?
[1] "slpDist"SAMPLE DESCRIPTIVES
Group by sex for overall sample.| Group | Female | Male | Total |
|---|---|---|---|
| HC | 27 | 23 | 50 |
| CLBP | 41 | 23 | 64 |
| FM | 39 | 5 | 44 |
| Total | 107 | 51 | 158 |
Means and SDs for each group.
Descriptive statistics by group
group: HC
vars n mean sd se
group.factor* 1 50 1.00 0.00 0.00
slpQual 2 50 0.76 0.62 0.09
slpLat 3 50 0.94 0.79 0.11
slpDur 4 50 0.80 0.70 0.10
slpEff 5 50 1.32 1.35 0.19
slpDayFcn 6 50 0.30 0.46 0.07
psqi_Global 7 50 5.38 2.70 0.38
ess_total 8 50 5.90 2.84 0.40
bdi_total 9 50 3.26 4.04 0.57
mcgill_total 10 50 1.56 6.20 0.88
------------------------------------------------------------
group: CLBP
vars n mean sd se
group.factor* 1 64 2.00 0.00 0.00
slpQual 2 64 1.20 0.78 0.10
slpLat 3 64 1.28 0.83 0.10
slpDur 4 64 0.86 0.71 0.09
slpEff 5 64 1.33 1.31 0.16
slpDayFcn 6 64 0.22 0.42 0.05
psqi_Global 7 64 6.47 2.83 0.35
ess_total 8 64 6.88 3.48 0.44
bdi_total 9 64 10.12 8.60 1.08
mcgill_total 10 64 24.94 14.93 1.87
------------------------------------------------------------
group: FM
vars n mean sd se
group.factor* 1 44 3.00 0.00 0.00
slpQual 2 44 1.77 0.74 0.11
slpLat 3 44 2.11 1.04 0.16
slpDur 4 44 1.43 1.00 0.15
slpEff 5 44 1.68 1.33 0.20
slpDayFcn 6 44 0.11 0.32 0.05
psqi_Global 7 44 9.75 3.86 0.58
ess_total 8 44 8.23 4.05 0.61
bdi_total 9 44 16.11 9.31 1.40
mcgill_total 10 44 35.57 13.12 1.98
------------------------------------------------------------
group: TRUE
NULL#PLOTS
CORR PLOTS
The end of corr plots
BAR PLOTS
BOX PLOTS
ANOVA (Main effect of group)
| Name | p.value |
|---|---|
| slpQual | 1.87e-09 |
| slpLat | 4.37e-09 |
| slpDur | 0.000197 |
| slpEff | 0.318 |
| slpDist | 0.0365 |
| slpMeds | 9.37e-09 |
| slpDayFcn | 0.0906 |
| psqi_Global | 4.43e-10 |
| ess_total | 0.00597 |
| isi_total | 7.57e-10 |
| bdi_total | 1.29e-12 |
| mcgill_total | 4.96e-28 |
| TIB | 0.865 |
| Note: | |
| Red = Significant main effect for group (p ≤ 0.05) |
POSTHOC
| contrast | null.value | diff | conf.low | conf.high | adj.p.value |
|---|---|---|---|---|---|
| Sleep Quality | |||||
| CLBP-HC | 0.000 | 0.443 | 0.120 | 0.766 | 0.00411 |
| FM-HC | 0.000 | 1.013 | 0.659 | 1.367 | 7.56e-10 |
| FM-CLBP | 0.000 | 0.570 | 0.234 | 0.905 | 0.000268 |
| Sleep Latency | |||||
| CLBP-HC | 0.000 | 0.341 | -0.052 | 0.735 | 0.103 |
| FM-HC | 0.000 | 1.174 | 0.743 | 1.604 | 4.1e-09 |
| FM-CLBP | 0.000 | 0.832 | 0.424 | 1.240 | 9.81e-06 |
| Sleep Duration | |||||
| CLBP-HC | 0.000 | 0.059 | -0.297 | 0.415 | 0.918 |
| FM-HC | 0.000 | 0.632 | 0.242 | 1.022 | 0.000535 |
| FM-CLBP | 0.000 | 0.572 | 0.203 | 0.942 | 0.00098 |
| Sleep Efficacy | |||||
| CLBP-HC | 0.000 | 0.008 | -0.584 | 0.600 | 0.999 |
| FM-HC | 0.000 | 0.362 | -0.287 | 1.010 | 0.386 |
| FM-CLBP | 0.000 | 0.354 | -0.261 | 0.968 | 0.363 |
| Sleep Disturbance | |||||
| CLBP-HC | 0.000 | 0.060 | -0.000 | 0.120 | 0.0512 |
| FM-HC | 0.000 | 0.060 | -0.006 | 0.126 | 0.0829 |
| FM-CLBP | 0.000 | 0.000 | -0.063 | 0.063 | 1 |
| Sleep Medications | |||||
| CLBP-HC | 0.000 | 0.258 | -0.208 | 0.724 | 0.391 |
| FM-HC | 0.000 | 1.316 | 0.806 | 1.827 | 2.38e-08 |
| FM-CLBP | 0.000 | 1.058 | 0.575 | 1.542 | 2.03e-06 |
| Sleep Daytime Functioning | |||||
| CLBP-HC | 0.000 | -0.081 | -0.264 | 0.101 | 0.544 |
| FM-HC | 0.000 | -0.186 | -0.386 | 0.013 | 0.0732 |
| FM-CLBP | 0.000 | -0.105 | -0.294 | 0.084 | 0.39 |
| PSQI Global | |||||
| CLBP-HC | 0.000 | 1.089 | -0.303 | 2.480 | 0.156 |
| FM-HC | 0.000 | 4.370 | 2.846 | 5.894 | 6.86e-10 |
| FM-CLBP | 0.000 | 3.281 | 1.838 | 4.725 | 8.11e-07 |
| ESS Total | |||||
| CLBP-HC | 0.000 | 0.975 | -0.574 | 2.524 | 0.299 |
| FM-HC | 0.000 | 2.327 | 0.631 | 4.023 | 0.00406 |
| FM-CLBP | 0.000 | 1.352 | -0.255 | 2.959 | 0.118 |
| ISI Total | |||||
| CLBP-HC | 0.000 | 4.171 | 0.547 | 7.794 | 0.0199 |
| FM-HC | 0.000 | 10.250 | 6.728 | 13.772 | 2.19e-09 |
| FM-CLBP | 0.000 | 6.079 | 3.080 | 9.079 | 1.64e-05 |
| BDI Total | |||||
| CLBP-HC | 0.000 | 6.865 | 3.426 | 10.304 | 1.53e-05 |
| FM-HC | 0.000 | 12.854 | 9.087 | 16.620 | 5.43e-13 |
| FM-CLBP | 0.000 | 5.989 | 2.420 | 9.557 | 0.00032 |
| McGill Total | |||||
| CLBP-HC | 0.000 | 23.378 | 17.897 | 28.858 | 1.42e-14 |
| FM-HC | 0.000 | 34.008 | 28.006 | 40.010 | 0 |
| FM-CLBP | 0.000 | 10.631 | 4.944 | 16.317 | 5.38e-05 |
| Time in Bed | |||||
| CLBP-HC | 0.000 | -0.439 | -5.355 | 4.476 | 0.976 |
| FM-HC | 0.000 | -1.215 | -6.598 | 4.168 | 0.855 |
| FM-CLBP | 0.000 | -0.776 | -5.876 | 4.324 | 0.931 |
| Note: | |||||
| Red = Significant group tests (p ≤ 0.05) | |||||
STOP HERE
ISI ANALYSES
This set of analyses uses a subset of subjects who have completed the ISI
Also create a dataset of subjects with ISI data (dat.isi).
ISI DATA VARIANCE
The variable(s) in the ISI data with variance issues are: